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A phase 2b clinical trial published in 2015 examined Larazotide in patients with celiac disease who continued to have symptoms despite following a gluten-free diet

The research focus is primarily on connective tissue injuries: tendons, ligaments, muscles, and joints

Back Raufman, J-P, Tensen, RT, Sutliff, VE, et al (May 1982) 'Actions of Gila monster venom dispersed from guinea pig pancreas', American Journal of Physiology , 242/5, G470-4

While this appears rare and may have been dose-related, kidney function monitoring is a reasonable safety measure

It has also shown its ability to increase collagen production, boost cellular energy, and support regenerative healing in muscle and tendon tissues