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The proteasome system is closely linked to mitochondrial remodeling in several physiological and disease states, including cancer [71, 72]
Flow cytometry using the DCFH-DA probe indicated that the marked elevation in ROS levels caused by the OGD and erastin treatments was rescued by the GSH treatment (Fig
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Their findings suggest that tissue-resident macrophages may exhibit unique pro-tumor functions, distinct from infiltrating monocytes that differentiate into macrophages within the tumor
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