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Therefore, the research has focused on new drugs that have been showed to have pleiotropic effects beyond hypoglycemic action
Most diets are high in calories and low in essential minerals and vitamins
Based on these mechanisms, emerging interventional strategies have been proposed to curb intercellular ferroptotic spread, including: blocking exosome-mediated signal transmission, inhibiting STING pathway activation, and enhancing astrocytic phagocytic and clearance functions
doi: 10.1172/JCI116186 30 NauckMAKleineNOrskovCHolstJJWillmsBCreutzfeldtW
He argued that the most transformative advances will come not from GLP-1 monotherapy, but from combinations that integrate multiple gut hormones and perhaps even extend beyond metabolism to address obesitys comorbidities
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