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NICE has published guidance on pharmacological interventions for weight management, including NICE guideline CG189 (Obesity: identification, assessment and management) and a technology appraisal supporting the use of semaglutide (Wegovy) for adults with a BMI of 35 kg/m or above (or 3034.9 kg/m in certain circumstances) alongside a specialist weight management service
Benjamini-Hochberg adjusted P ( d - i )
GIP (glucose-dependent insulinotropic polypeptide) was once considered primarily an incretin hormone, but research has revealed its broader metabolic role
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