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While previous studies have shown that CNS GABAergic neurons are necessary for the food intake- and body weight-reducing effects of GIPR agonists 5,11 , the anatomic region that underlies these effects remains unknown
~5-fold potency at GIPR relative to native GIP
doi: 10.3390/nu15092080
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First, routine screening for vitamin B12 deficiency should be incorporated into primary care for high-risk populations such as older adults, women of reproductive age, vegetarians, and patients with diabetes or chronic use of metformin or proton pump inhibitors
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