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Increased frequency of intentional weight loss associated with reduced mortality: a prospective cohort analysis
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Wegovy is a medication approved for the treatment of obesity in the UK
459,460 The anti-inflammatory effects of GLP-1RAs contribute to the attenuation of atherosclerotic plaque lesion development through various mechanisms
Conclusion The latest evidence supports GLP-1-based therapy as one of the most effective current pharmacologic strategies for type 2 diabetes and obesity, with tirzepatide showing the strongest comparative performance for HbA1c reduction and weight loss and semaglutide and liraglutide remaining highly effective established options (Fras et al., 2021), (Karagiannis et al., 2024), (Nauck et al., 2021)
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