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With a half-life around 5 days, tirzepatide is essentially cleared about 4 to 5 weeks after the final dose
For chronic conditions, some people use longer cycles
GLP-1-based therapies have also been linked to more severe, albeit rare, gastrointestinal side effects, including intestinal obstruction and symptomatic gastroparesis [121]
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While 10 days is closer to the recommended schedule than 14, it is still considered off-label
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