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The Institute for Clinical and Economic Review (ICER) in 2025 noted that price reductions and long-term benefits have improved GLP-1 cost-effectiveness relative to older assumptions ( [70] ), yet insurers still face high absolute spend
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The additional 5% weight loss Zepbound might provide (based on trial averages) may not materialize for this individual, and the switch could disrupt a working treatment plan
Mills, D
