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Moreover, a comparison of the number of animals with unhealed defects (all controls) or healed defects (complete bony continuity across the defect site) showed that besides pentadecapeptide intramuscular application for 14 days (i.e., local application of bone marrow or autologous cortical graft), also following other pentadecapeptide BPC-157 regimens (local application, or intermittent intramuscular administration), the number of animals with healed defect was increased
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BPC-157 has been extensively investigated in laboratory and preclinical research examining tissue biology, angiogenesis, gastrointestinal physiology and cellular signalling pathways
Subcutaneous injection and oral capsules, the two most common human routes, have not been studied with the same rigor in animals
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