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In the foundational characterization by Raun and colleagues, it released GH with a potency comparable to GHRP-6, but with one decisive difference: Ipamorelin raised neither ACTH nor cortisol and did not affect FSH, LH, prolactin and TSH (Raun et al., 1998)
These limitations can be more appropriately addressed in future systematic reviews with meta-analyses
The medication works by mimicking a naturally occurring hormone called glucagon-like peptide-1 (GLP-1)
The move was audacious on multiple levels
10.1038/nrm3904 Nat
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