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Primary antibody (anti-GCSc 1:10 (SantaCruz, sc390811) and anti-CD45 1:200 (Proteintech, 31243-1-AP)) incubation was carried out overnight at 4 C
These assumptions allow for the calculation of the intermediate respiratory state or state apparent (Supplementary Fig
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The principle of using mAbs to increase IgG catabolism was also demonstrated in NHPs, when Nixon and colleagues at Dyax Corp used phage-display selected human IgG1 mAbs with high pH-independent affinity towards FcRn to reduce circulatory IgG without affecting albumin levels in NHPs [122]
Yang RK, Qing Y, Jelloul FZ, Routbort MJ, Wang P, Shaw K, Zhang J, Lee J, Medeiros LJ, Kopetz S , Tetzlaff MT, Broaddus RR
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