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Other recognised adverse effects include: Injection site reactions (redness, itching) Fatigue (uncommon) Dizziness (uncommon) A modest increase in heart rate has been observed Gallbladder disorders , including cholecystitis and cholelithiasis Diabetic retinopathy complications (particularly in patients with pre-existing retinopathy and rapid improvement in glycaemic control) Acute pancreatitis (uncommon) Dysgeusia (taste disturbance) Increases in pancreatic enzymes (amylase/lipase) Serious allergic reactions, though rare, require immediate medical attention

We included studies involving adult patients aged 18 years or older using GLP-1 agonists

20 There is no identified causal agent for SjD and it presents with multiple organ involvement

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[7] revealed the potential of senolytic treatments for canine aging