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Recently, sodium-glucose co-transporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) have emerged as a new class of drugs designed to treat patients with type 2 diabetes (T2D), but have also been shown to be protective against HF-related events and CV mortality
Smith MH, Ploegh HL, Weissman JS (2011) Road to ruin: targeting proteins for degradation in the endoplasmic reticulum
It is a GLP-1 agonist that works by reducing hunger and helping the stomach empty by increasing insulin secretion and decreasing glucagon secretion
Many patients notice improvements in energy and recovery within the first few weeks, but the cellular marker improvement is dependent on baseline oxidative stress
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