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However, laser liposuction does not remove visceral fat, which is the deeper fat that surrounds internal organs

The research above (Badenhorst, Finkley, Abdulghani, Carey/Pickart) all studied topical application

For a drug to passively diffuse through this layer, it typically needs to be: Small in molecular size Lipophilic (fat-soluble) However, GLP-1 molecules: Are too large and hydrophilic Cannot naturally penetrate the skin barrier Even if GLP-1 patches claim to have GLP-1 drugs, the molecules cannot pass through the skin barrier without support

But the range for what's "normal" is debatable, so it's recommended to use at least two testing methods