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Semaglutide, particularly at higher doses, has demonstrated greater weight loss results and is often preferred for more intensive glycemic control
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S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2
peas, beans, chickpeas, lentils) Nuts and seeds (e.g
Karmiris K, Avgerinos A, Tavernaraki A et al (2016) Prevalence and characteristics of extra-intestinal manifestations in a large cohort of greek patients with inflammatory bowel disease
![Cardiovascular disease continuum-GLP-1 action. Adapted from [46]](https://www.researchgate.net/publication/357072789/figure/fig1/AS:1146405179654167@1650335702879/Cardiovascular-disease-continuum-GLP-1-action-Adapted-from-46.png)
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