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Reduced Side Effects One of the most significant benefits of microdosing is improved tolerability
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To avoid intestinal degradation and diarrhea, pharmaceutical companies sought to develop an oral SGLTi to specifically target renal glucose reabsorption
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Control over engineered biological systems, reliant on specific inputs, can be achieved at the transcriptional 8,9,10 , translational 11,12 or post-translational level 13,14,15,16,17 , with transcriptionally controlled systems being the most widely adopted due to their robustness 18,19
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