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Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)
Direct clinical trials specifically testing GLP-1 agents with oral contraceptives are limited, which is why providers take a cautious approach
(see codes in Supplementary Table S1) The follow-up period for all outcomes was defined as starting one day after the index fertility event and continuing for up to three years (1,095 days)
Enterohormonal changes after digestive adaptation: five-year results of a surgical proposal to treat obesity and associated diseases
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