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For example, while NAION nearly always presents only in one eye at a time, some patients presented with it in both eyes at the same time

Weight loss at 80 weeks (efficacy estimand): A1C at 80 weeks , from a baseline of 7.7%: -1.4% at 4 mg, -1.6% at 9 mg and -1.5% at 12 mg, versus -0.2% on placebo

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