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You can be in very good health and have excess weight, she says

Enhanced Wound Healing A 2024 Johns Hopkins study found that diabetic patients on GLP-1 drugs healed foot ulcers 30% faster than those on traditional therapies

Safety Profile (Phase 2) The most common adverse events were gastrointestinal and consistent with the incretin drug class: - Nausea - Diarrhea - Vomiting - Constipation - Decreased appetite These GI events were dose-related, mostly mild to moderate, and partially mitigated by starting at a lower initial dose (2 mg vs

This has several important implications for manufacturers: Early launch benchmarks may understate success if they focus primarily on switching behavior rather than new-to-therapy initiation The addressable market for oral GLP-1s may be larger than previously modeled , particularly if similar barriers exist across obesity and cardiometabolic indications Pipeline assets following oral semaglutide may enter a more receptive market , where the viability of oral administration has already been established What Great Looks Like: Speed and Clinical Depth at Launch Imagine if, within weeks of launch, pharma leaders could understand the earliest signals of launch performanceincluding prescription activity, patient flow, site of care, and early access dynamicsby assessing near-real-time, large-scale claims and EMR data

We spoke to three of them about what went wrong and what they wish they'd known before they started