tirzepatide muscle wasting Does Affect Mass? What You Need to Know Muscle loss side effect :

Increased heart rate: Semaglutide can increase your heart rate while you are at rest

And participants taking the semaglutide lost about 14% of their body weight, and they had significantly greater reductions in knee pain and improvements in physical function compared with the placebo group

Weight loss expectations Cumulative weight loss by week twenty: 10 to 18 percent of starting body weight

reported that the beta-cells of diabetic mice treated with Exendin-4 had decreased expression of markers of ER stress (111)

Conversely, some GLP-1 specific effects might feel different or delayed as your body adjusts to the new receptor balance