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With direct hGH injections, especially at high doses, theres a risk of excessively elevated GH/IGF-1 levels, which may lead to side effects like joint pain, edema, insulin resistance, or carpal tunnel syndrome
Given their clinical benefits and high price tags, GLP-1 RAs exemplify a tension in drug coverage: broad therapeutic value versus cost-containment
11 Glucose metabolism Obesity plays an important role in the risk of T2DM in individuals with PWS, as in the general population (171, 173, 181)
participants should not adjust their dose independently Antiemetics : A clinician may consider short-term antiemetic treatment if nausea is significant For concerns related to muscle mass preservation , incorporating resistance exercise and ensuring adequate dietary protein intake are evidence-based strategies that may help mitigate lean tissue loss during significant weight reduction
[3] It is not recommended in type 1 diabetes
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