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A patient can finish a course of GLP-1 treatment significantly lighter and simultaneously in a weaker metabolic position than when they started if muscle preservation was not part of the plan. This is the mechanism behind what clinicians commonly observe in weight cycling
Though rare, allergic reactions can occur
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glipizide as add-on therapy in patients with type 2 diabetes mellitus inadequately controlled on metformin alone: long-term (52-week) extension of a 52-week randomised controlled trial
doi: 10.1210/jc.2019-00710 21 LiuJLiJLiSLengJLiWYangWet al
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