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9-12 Many studies have investigated the role of GLP-1 RAs on the risk of ophthalmic diseases, including diabetic retinopathy (DR), glaucoma, AMD, idiopathic intracranial hypertension (IIH), and nonarteritic anterior ischemic optic neuropathy (NAION)
Chronic iron load also promotes macrophage polarization towards the M1 type, inhibiting the M2/resolving phenotype, weakening the fine-tuning ability of tissue repair and fibrosis, and causing the COPD immune microenvironment to remain in a low but persistent pro-inflammatory state (121)
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One study found that higher levels of glutathione peroxidase, an enzyme dependent on glutathione, were associated with a lower risk of heart attacks
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