Endocrinology 166 (4), bqaf028
Abstract Lactate, traditionally considered just a byproduct of metabolism, is now understood to be a vital regulator in energy metabolism, immune function, and epigenetic changes
Anti-anxiety effects in rats at 0.5 g/kg (extremely low dose) produced effects within 12 minutes of intraperitoneal injection, including increased time exploring open/lighted maze areas, decreased immobile freeze reaction time, and increased exploration in open field tests
demand has also triggered global shortages that hinder the drugs availability for essential diabetes care in LMICs
This class of drugs have been around for 20+ years so we do know the most common side effects are GI in nature (nausea, vomiting, constipation and diarrhea), Kaplan said