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They belong to the same class of heme-free thiol peroxidases as peroxidases and catalyze the reduction of H 2 O 2 or organic hydroperoxides to water or corresponding alcohols, thereby mitigating their toxicity (Zhao et al., 2019)
21 However, all of the sclerosing agents examined were directly toxic to both granulocytes and red blood cells (RBCs) at dilutions of up to 1 : 1000
doi: 10.1111/jfpe.12432 38
We do not prescribe the 25mg formulation as a starting dose without clinical justification
What happens with extended use over months or years is unknown territory
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