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At 72 weeks, the mean reduction in HbA1c was 1.29 percentage points with 6 mg orforglipron, 1.6 percentage points with the 12 mg dose and 1.78 percentage points with 36 mg orforglipron vs
Guimares FJS1
G.De WaeleJ
After a lifetime of using food to help manage my emotions, and then using restriction to help manage my emotions, I was always using one or the other, she says
In practice, patients on combined protocols report better strength retention and less metabolic slowdown compared to tirzepatide monotherapy, but these are subjective, uncontrolled observations
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