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Additionally, the researchers found that GEP44 exhibits biased agonism at the Y2-R, as documented by its inability to induce Y2-R-mediated increases in intracellular Ca2+ or ERK1/2 phosphorylation

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How it compares to Mounjaro and Wegovy The most useful comparison is what the main Phase 3 trials of each medication have shown for weight loss in adults without type 2 diabetes