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Consistent with the effects in rat PSCs, high glucose and TGF1 levels enhanced the proliferation and decreased the apoptosis of PSCs in the LG group, whereas GSH and SB431542 prevented the effects induced by high glucose

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This disulfide between Cys 35 and Cys 48 adopts a much higher energy cis GGS conformation (Haworth et al., 2007)

81 Additionally, DLST-mediated succinylation of PDHA1 at K83 enhances PDH activity and -KG accumulation, which activates OXGR1MAPK/ERK signaling in TAMs, suppressing MHC-II expression and T-cell priming