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Your clinician will review your full health history to determine if this treatment is appropriate for you

Targeting the dopamine D1 receptor or its downstream signalling by inhibiting phosphodiesterase-1 improves cognitive performance

Comparison of treatments was performed on a within-subject level (each mouse was its own control) and at least 1 week elapsed between each testing condition (drug or control treatment)

Accurate characterization of fatigue in patients taking GLP-1 receptor agonists requires careful clinical assessment to distinguish true fatigue from related symptoms and to identify potentially serious underlying causes

Prespecified subgroup analyses were stratified by duration of GLP1-RA or DPP4i use (at least 6-months, 1-year, and 2-years of use) within their respective groups