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Advantage: Potential for higher bioavailability than standard oral ingestion Challenge: Peptides are poorly absorbed through intact mucosal membranes without transport mechanisms Evidence: No studies confirm enhanced sublingual bioavailability for Dihexa Standard oral (swallowed): Tablets swallowed with water, absorbed through the gastrointestinal tract
People with a family history of bowel cancer should ask about surveillance
Expression of the SVCT2 transporter in the brain is critical for normal brain function and for ascorbate homeostasis within the brain
PMID: 20232164
Bartels LE, Bendix M, Hvas CL, et al
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