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Reduction of cardiovascular risk in selected adults with established cardiovascular disease and obesity or overweight, when specifically prescribed
Risk increases with time beyond the expiration date
These L-cells are equipped with specific G-protein-coupled receptors, namely FFAR2 (GPR43) and FFAR3 (GPR41), which are biologically designed to "taste" microbial metabolites
Philp D et al
2018: A double-blind, placebo-controlled study among women receiving taxane-based chemotherapy to treat breast cancer found that 3 grams of acetyl-L-carnitine taken daily for 5.5 months significantly WORSENED symptoms of chemotherapy-induced peripheral neuropathy compared to placebo, and this difference persisted after 2 years [7][28]
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