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Today, GLP-1 drugs, including Wegovy, Mounjaro and Zepbound, have become household names and key tools in the fight against obesity: 1 in 8 American adults say they have used a GLP-1 drug, and forecasts show that by 2030, 1 in 10 Americans will likely be using these medications

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At UAB, scientists are working to understand not just that these medications work, but how they work: how they act in the brain, how they affect multiple organs at once, why some patients respond better than others and what next-generation versions of these drugs might look like