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The 5272 hairs in this study significantly exceeds those numbers, though direct comparison requires caution because patient populations, measurement methods, and baseline conditions differ

Clin Chim Acta 2005;360:173-7

With increasing intakes of vitamin B12, concentrations of holoTC rise continuously at least until vitamin B12 saturates the transport proteins

Am J Physiol 263: C1181C1189

In cases of long-standing or severe deficiency, nerve damage may be partially irreversible, highlighting the importance of early detection and treatment