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Even a few hours above 8 degrees Celsius accelerates degradation significantly

On the other hand, when comparing the GLP1-RAs and SGLT2is combination to SGLT2is alone, there was a 29% reduction in the risk of MACE (7.6 vs 10.7 events per 1000 person-years

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10.1016/j.metabol.2013.01.014 113 ThomasC.GioielloA.NoriegaL.StrehleA.OuryJ.RizzoG.et al (2009)

They solve different phases of the same problem: one repairs tissue at the site of injury, the other resets the inflammatory environment throughout the body