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The application seeks approval for chronic weight management in adults with obesity, defined as a body mass index of 30 or above, or overweight at a BMI of 27 or above with at least one weight-related comorbidity, as an adjunct to a reduced-calorie diet and increased physical activity

Some patients notice sleep changes earlier, while body composition changes tend to develop more gradually

Steurer, M

Children : Paediatric use should only occur under specialist supervision, typically in diagnosed deficiency states or specific metabolic disorders

If your assay buffer contains reducing agents, dilute from a peptide stock prepared in a separate, reducing-agent-free diluent