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The oral drugs work much the same way as the injectables, says Louis Aronne, MD, the Sanford I
Human Evidence Human research primarily involves topical application
This phase 3 randomized controlled trial enrolled participants with BMI over 24 kg/m (the obesity threshold in Asian populations) or BMI over 28 kg/m with comorbidities
Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model
These findings support biological delivery, but they do not establish that one form produces better clinical outcomes
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