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Consistent with a general effect on BCAA catabolism, Mmut p.L690Ins/p.L690Ins mice treated with BCATi accumulated unlabeled valine, leucine, and isoleucine in muscle, liver, and plasma compared with untreated wild-type and Mmut p.L690Ins/p.L690Ins mice (Supplemental Figure 5, AC)
Plant-based foods contain minimal L-Carnitine, which is why supplementation often appeals to vegetarians and vegans
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