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Low folate levels (from an MTHFR variation) can lead to low SAMe, a molecule that controls how quickly your body breaks down histamine
10.1016/j.lfs.2018.11.041 88 PangL.LianX.LiuH.ZhangY.LiQ.CaiY.et al (2020)
Critical markers during combined use IGF-1 levels: Check every 4 weeks for the first 12 weeks, then every 8 weeks if stable
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