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193 Furthermore, combining DDR inhibitors with ICB enhances antitumor immunity by promoting neoantigen exposure, micronuclei formation, and activation of the cGASSTING pathway

Poor responders or those with particularly stubborn chronic conditions may benefit from longer treatment phases before breaks

Liposomal encapsulation further enhances this dual-action pathway by simultaneously shielding the cell from ROS and fueling ATP production

Higher doses (5mg twice weekly) used for severe injuries or accelerated healing timelines

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