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Regarding altered neuronal/synaptic activity, a reduced glutamatergic projection from ACC to the ventral hippocampal CA1 area is suggested to contribute to depressive-like symptoms in 3-month-old 5xFAD mice (Kim et al., 2023)
It is intended to be administered by subcutaneous or intramuscular injection
For training, many take one dose an hour before and another later in the day
Animals were supplied with normal food and water ad libitum
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