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Dose Reduction Framework Step 1: Reach Goal Weight on Full Dose Stay on your maximum effective dose (typically 8-12mg weekly) until youve maintained your goal weight for 8-12 weeks

SHBG Changes Weight loss and improved metabolic health may increase sex hormone-binding globulin (SHBG), which helps regulate circulating testosterone and supports a healthier balance of free (active) hormone

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The compound combines balanced agonist activity across all three target receptors with structural modifications Aib substitutions and C20 fatty diacid acylation that extend half-life through albumin binding

Difficulty losing weight through diet and exercise alone