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Assessing the proportional hazards assumption, there was no significant interaction between follow-up time and use of GLP1 receptor agonists (P=0.82)

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Topical collagen: Topical treatments called "collagen creams" frequently comprise intact collagen (too large to penetrate skin), hydrolyzed collagen fragments (slightly smaller), and collagen-stimulating chemicals (peptides, retinoids)

Reports of emotional blunting and loss of pleasure come largely from individual patient experiences, post-marketing observations and emerging research into how GLP-1 signalling interacts with the brain

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