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In sum, the response of the FSHR-LIN-12 NRR -Notch receptor in the Drosophila MAPS assay parallels that of the response of the LIN-12 receptor to LAG-2 and APX-1 signaling in C
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For patients with diabetes, preserving muscle is especially important because skeletal muscle plays a key role in glucose disposal and insulin sensitivity
Having more control over the pace and dose could help mitigate potential side effects associated with the medication at therapeutic doses, such as nausea, diarrhea and constipation
Treatment duration should be based on ongoing benefit and tolerability, with limited data available beyond 2 years of use
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