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In these clinical trials, 42% of patients lost 5% or more of their body weight, 21% of patients lost 10% or more, and 10% of patients lost 15% or more

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There are only two GLP-1 agonists that are TGA approved for weight loss, semaglutide (Wegovy brand) and liraglutide (Saxenda)

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These findings suggest that GIP but not GLP-1RA may improve glucose disposal by ameliorating peripheral insulin sensibility and glucose utilization, while GIP added on to GLP-1RA may reduce food intake with a combined effect resulting in improvement of glucose control and weight loss

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