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Both the Food and Drug Administration (FDA) and the European Medicines Agency are actively monitoring the psychiatric safety of semaglutide and similar medications after post marketing surveillance reports of depression, suicidal thoughts (ideation), and suicidal behavior in patients taking the drugs for the management of type 2 diabetes or obesity

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El-Beltagi, H., Salama, Z

Researchers use the peptide to compare lipolytic and lipogenic balance under combined incretin/glucagon signaling versus single-pathway controls