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Two percent pushes toward the upper limit of what most dermatologists recommend for unsupervised home use

Researchers are responsible for establishing suitable storage, documentation, protective equipment, and handling controls

USP Compounding Standards and Beyond-Use Dates (BUDs) (PDF)

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Patients taking certain medications (e.g., chloramphenicol may reduce the effectiveness of B12 therapy) or with risk factors for B12 deficiency (metformin use, proton pump inhibitors, nitrous oxide exposure, vegan diet) should discuss these with their healthcare provider