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[37] [38] When internalized by endocytosis, nanogels encounter high concentrations of GSH inside the cancer cell
Lipoic acid might be able to increase glutathione synthesis in aged rats by up-regulating the expression of -glutamylcysteine ligase (-GCL), the rate-limiting enzyme in glutathione synthesis (31), and by increasing cellular uptake of cysteine, an amino acid required for glutathione synthesis (32)
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Hill et al., 2025)
