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In contrast, a sedentary lifestyle is associated with increased levels of oxidative stress

Epithalon's epigenetic regulation might involve competitive binding with histones at DNA interaction sites, increasing transcription of genes involved in neuronal differentiation

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The pathogenesis of AD arises from a multifactorial interplay, involving abnormalities in the structure of the vascular wall, hypertension, inflammation, oxidative stress, apoptosis, ferroptosis, and various genetic mutations (Vilacosta et al., 2010

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