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Additionally, the rats were during these days exposed to HFD for 2 hours or chow (timed with the initial exposure to alcohol): creating four treatment groups (vehicle-chow, vehicle-HFD, semaglutide-chow, and semaglutide-HFD) (see Figure 3A for timeline)
This is crucial because elevated testosterone levels contribute to common PCOS symptoms like irregular periods and excess facial hair
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So this hormonal change within our intestinal system turns out to be incredibly powerful signals that work neurologically and through endocrine fashion up to the brain that really tell us how to regulate our body fat
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