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Puerarin alleviates depressive-like behaviors in high-fat diet-induced diabetic mice via modulating hippocampal GLP-1R/BDNF/TrkB signaling

The primary clinical concerns involve gastrointestinal (GI) side effects leading to dehydration, delayed gastric emptying affecting oral medication absorption, and increased aspiration risk during sedated procedures

May help protect neurons from oxidative or inflammatory damage

Peters KM, Jaeger C, Killinger KA et al: Cystectomy for ulcerative interstitial cystitis: Sequelae and patients' perceptions of improvement